CornCyc and MaizeCyc are comprehensive metabolic pathway resources developed using the Pathway Tools Software Suite in collaboration between MaizeGDB, the Plant Metabolic Network (PMN) (CornCyc), and Gramene (MaizeCyc). MaizeGDB curators performed literature-based manual annotation for both resources.

While CornCyc and MaizeCyc are generated using the same Pathway Tools Software Suite to generate their respective data sets, they differ in the number of pathways, enzymes, and enzymatic reactions. This is mainly due to their respective methods of assigning enzymatic function. You can find more information about both resources in the "Information and Tutorials" section below.

• Comparison of CornCyc and MaizeCyc resources
• How to install Pathway Tools and visualize Cyc resources locally
• How to visualize your RNA-seq data using Pathway Tools interface at MaizeGDB
• Video Tutorial on metabolic pathways at Gramene

• MaizeCyc paper and Supplementary materials
• MaizeCyc resource files for local installation (see the Pathway Tools installation directions above)
• CornCyc resource files for local installation (see the Pathway Tools installation directions above)
• Example data from Sekhon et al, Plant Journal, 2011
• Go terms associated with gene models.

• Plant Metabolic Network
• Gramene
• Webinars at BioCyc

Although MaizeCyc and CornCyc are both great resources, they are unfortunately incomplete and contain misannotations. MaizeGDB curators continuously perform literature-based manual curations to add new annotations and remove the incorrect ones. With your expertise and help, we can do much better. If you see any information in MaizeCyc or CornCyc that is wrong, please use the feedback link at the top of the page to contact us. We will appreciate your input, and the maize community will greatly benefit from your suggestions.